Harsh Singh Rajput 
Introduction Atogepant is an oral migraine-preventive drug that belongs to the calcitonin gene-related peptide receptor antagonist class. Drugs in this class are commonly called gepants. Atogepant is marketed under the brand name Qulipta in the United States and Aquipta in some other regions. Atogepant is used for the preventive treatment of migraine in adults. It … Read more
Introduction Cladribine is a purine nucleoside analogue used as an immunosuppressive and antineoplastic drug. It is available under important brand names such as Mavenclad for relapsing forms of multiple sclerosis and Leustatin for hairy cell leukemia. Pharmacologically, cladribine is an adenosine analogue that is resistant to degradation by adenosine deaminase, allowing it to persist inside … Read more
Introduction Brilinta is the brand name of ticagrelor, an oral antiplatelet drug used mainly to prevent thrombotic cardiovascular and cerebrovascular events. It belongs to the P2Y12 platelet receptor inhibitor class and is commonly used in patients with acute coronary syndrome, history of myocardial infarction, coronary artery disease at high risk of thrombotic events, and selected … Read more
Introduction Eltrombopag is an oral thrombopoietin receptor agonist used to increase platelet production in selected patients with thrombocytopenia. It is marketed under the brand name Promacta in the United States and Revolade in some other countries. Pharmacologically, eltrombopag is classified as a non-peptide thrombopoietin receptor agonist. Thrombopoietin, also called TPO, is the natural hormone that … Read more
Introduction Lurbinectedin is an intravenous anticancer drug marketed under the brand name Zepzelca. It belongs to the class of alkylating antineoplastic agents and is mainly used in small cell lung cancer, a highly aggressive neuroendocrine lung cancer that often responds initially to platinum-based chemotherapy but commonly relapses. Lurbinectedin is pharmacologically important because it targets DNA … Read more
Introduction Ibrance is the brand name of palbociclib, an oral targeted anticancer drug belonging to the class of cyclin-dependent kinase 4 and 6 inhibitors, commonly called CDK4/6 inhibitors. It is mainly used in hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced or metastatic breast cancer. Ibrance is pharmacologically important because it targets a key … Read more
Introduction Mavacamten is an oral cardiac myosin inhibitor marketed under the brand name Camzyos. It is used for the treatment of adults with symptomatic New York Heart Association class II–III obstructive hypertrophic cardiomyopathy, also called obstructive HCM or oHCM, to improve functional capacity and symptoms. Current prescribing information describes Camzyos as a cardiac myosin inhibitor … Read more
Introduction Canakinumab is a recombinant human monoclonal antibody used as a targeted anti-inflammatory biologic. It is marketed under the brand name Ilaris and belongs to the class of interleukin-1 beta inhibitors. Canakinumab specifically blocks interleukin-1 beta, also written as IL-1β, a powerful pro-inflammatory cytokine involved in fever, neutrophil recruitment, acute-phase response, joint inflammation, systemic inflammation, … Read more
Introduction Xiidra is the brand name of lifitegrast ophthalmic solution 5%, a prescription eye drop used for the treatment of signs and symptoms of dry eye disease. Dry eye disease is a chronic inflammatory condition of the ocular surface in which tear film instability, inflammation, epithelial stress, and immune-cell activation contribute to dryness, burning, irritation, … Read more
Introduction Opzelura is the brand name of ruxolitinib cream, a topical Janus kinase inhibitor used in inflammatory and autoimmune skin diseases. It contains ruxolitinib phosphate and is available as a 1.5% cream for application to affected skin areas. Opzelura is indicated for the short-term and non-continuous chronic treatment of mild to moderate atopic dermatitis in … Read more
