Harsh Singh Rajput

Introduction Avacopan is an oral immunology drug marketed under the brand name Tavneos. Pharmacologically, avacopan is a complement 5a receptor antagonist, commonly written as a C5aR antagonist. Anti-neutrophil cytoplasmic autoantibody-associated vasculitis, or ANCA-associated vasculitis, is an autoimmune small-vessel vasculitis. It includes granulomatosis with polyangiitis, also called GPA, and microscopic polyangiitis, also called MPA. In these … Read more

Introduction Ingrezza is the brand name of valbenazine, an oral drug used for movement disorders caused by abnormal monoamine signaling in the brain. Pharmacologically, valbenazine is a vesicular monoamine transporter 2 inhibitor, commonly called a VMAT2 inhibitor. VMAT2 is a transporter present on synaptic vesicles inside presynaptic neurons. Its normal role is to move monoamine … Read more