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Mechanism of Action of Bendamustine

Mechanism of Action of Bendamustine

Introduction Bendamustine is an anticancer drug used mainly in certain hematologic malignancies. Pharmacologically, bendamustine is an alkylating agent and a bifunctional mechlorethamine derivative. Bendamustine hydrochloride is given by intravenous infusion. It is used in chronic lymphocytic leukemia, commonly called CLL, and indolent B-cell non-Hodgkin lymphoma, commonly called NHL, that has progressed during or within six … Read more

Mechanism of Action of Lurbinectedin

Mechanism of Action of Lurbinectedin

Introduction Lurbinectedin is an intravenous anticancer drug marketed under the brand name Zepzelca. It belongs to the class of alkylating antineoplastic agents and is mainly used in small cell lung cancer, a highly aggressive neuroendocrine lung cancer that often responds initially to platinum-based chemotherapy but commonly relapses. Lurbinectedin is pharmacologically important because it targets DNA … Read more

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