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Mechanism of Action of Tenapanor

Mechanism of Action of Tenapanor

Introduction Tenapanor is an oral, locally acting gastrointestinal drug marketed under two important brand names: Ibsrela and Xphozah. Pharmacologically, tenapanor is a sodium/hydrogen exchanger 3 inhibitor, commonly written as an NHE3 inhibitor. NHE3 is an antiporter located on the apical surface of intestinal epithelial cells in the small intestine and colon. It plays an important … Read more

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