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Mechanism of Action of Patiromer

Mechanism of Action of Patiromer

Introduction Patiromer is an oral potassium-binding drug marketed under the brand name Veltassa. Pharmacologically, patiromer is a non-absorbed cation exchange polymer used for the treatment of hyperkalemia. Hyperkalemia means increased serum potassium concentration. Potassium is essential for normal nerve conduction, skeletal muscle contraction, and cardiac electrical activity. However, excessive potassium can disturb cardiac conduction and … Read more

Mechanism of Action of Kerendia (Finerenone)

Mechanism of Action of Kerendia

Introduction Kerendia is the brand name for finerenone, a non-steroidal selective mineralocorticoid receptor antagonist (MRA) used to reduce the risk of chronic kidney disease (CKD) progression and cardiovascular complications in adults with chronic kidney disease associated with type 2 diabetes mellitus. Unlike older steroidal MRAs such as spironolactone and eplerenone, finerenone has a unique non-steroidal … Read more

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