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Mechanism of Action of Vtama

Mechanism of Action of Vtama

Introduction Vtama is the brand name of tapinarof cream 1%, a topical non-steroidal dermatological drug used in inflammatory skin diseases. It belongs to the class of aryl hydrocarbon receptor agonists, commonly abbreviated as AhR agonists. Vtama is indicated for the topical treatment of plaque psoriasis in adults and atopic dermatitis in adults and pediatric patients … Read more

Mechanism of Action of Cosentyx

Introduction Cosentyx is the brand name of secukinumab, a fully human monoclonal antibody used in immune-mediated inflammatory diseases. It belongs to the class of interleukin-17A inhibitors, also called IL-17A antagonists. Cosentyx is important in pharmacology because it targets a specific inflammatory cytokine rather than producing broad immunosuppression like corticosteroids. It is used in conditions where … Read more

Mechanism of Action of Stelara (Ustekinumab)

Mechanism of action of Stelara

Introduction Stelara (ustekinumab) is a fully human IgG1κ monoclonal antibody designed to target key cytokines involved in immune-mediated diseases. It selectively binds to the p40 subunit common to interleukin-12 (IL-12) and interleukin-23 (IL-23), blocking their interaction with cell surface receptors. Stelara is approved for several chronic inflammatory conditions including plaque psoriasis, psoriatic arthritis, Crohn’s disease, … Read more

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