Mechanism of Action of Vedolizumab (Entyvio)
Introduction Vedolizumab is a humanized IgG1 monoclonal antibody used for the treatment of moderate to severe ulcerative colitis … Read more
Crohn’s Disease
Mechanism of Action of Infliximab (Remicade)
Introduction Infliximab is a chimeric (murine-human) IgG1 monoclonal antibody that targets tumor necrosis factor‑α (TNF‑α). It is used … Read more
Mechanism of Action of Natalizumab (Tysabri)
Introduction Natalizumab is a humanized IgG4 monoclonal antibody targeting the α4 integrin subunit. It’s approved for relapsing-remitting multiple … Read more
Mechanism of Action of Adalimumab (Humira)
Introduction Adalimumab is a fully human monoclonal IgG1 antibody that specifically targets tumor necrosis factor‑α (TNF‑α). By neutralizing … Read more
Mechanism of Action of Entyvio (Vedolizumab)
Introduction Entyvio (vedolizumab) is a recombinant humanized IgG1 monoclonal antibody that targets the α4β7 integrin on gut-homing T-lymphocytes. … Read more
Mechanism of Action of Stelara (Ustekinumab)
Introduction Stelara (ustekinumab) is a fully human IgG1κ monoclonal antibody designed to target key cytokines involved in immune-mediated … Read more