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Mechanism of Action of Opzelura

Mechanism of Action of Opzelura

Introduction Opzelura is the brand name of ruxolitinib cream, a topical Janus kinase inhibitor used in inflammatory and autoimmune skin diseases. It contains ruxolitinib phosphate and is available as a 1.5% cream for application to affected skin areas. Opzelura is indicated for the short-term and non-continuous chronic treatment of mild to moderate atopic dermatitis in … Read more

Mechanism of Action of Vtama

Mechanism of Action of Vtama

Introduction Vtama is the brand name of tapinarof cream 1%, a topical non-steroidal dermatological drug used in inflammatory skin diseases. It belongs to the class of aryl hydrocarbon receptor agonists, commonly abbreviated as AhR agonists. Vtama is indicated for the topical treatment of plaque psoriasis in adults and atopic dermatitis in adults and pediatric patients … Read more

Mechanism of Action of Otezla (Apremilast)

Mechanism of Action of Otezla

Mechanism of Action of Otezla (Apremilast) Introduction Otezla is the brand name for apremilast, an oral phosphodiesterase-4 (PDE4) inhibitor used for the treatment of plaque psoriasis, psoriatic arthritis, oral ulcers associated with Behçet’s disease, and other inflammatory conditions. Unlike biologic therapies that target specific cytokines, apremilast works intracellularly by modulating inflammatory signaling pathways through cyclic … Read more

Mechanism of Action of Benzoyl Peroxide

MOA of Benzoyl Peroxide

Introduction Benzoyl peroxide is a topical antimicrobial and keratolytic agent widely used in the management of acne vulgaris. It is considered a first-line therapy for comedonal, inflammatory, and mild-to-moderate acne. Benzoyl peroxide is known for its powerful bactericidal activity, ability to reduce sebum, and its capacity to prevent antibiotic resistance when used with topical or … Read more

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