dermatology pharmacology - Pharmacy Freak

Mechanism of Action of Otezla (Apremilast)

June 19, 2026 Harsh Singh Rajput

Mechanism of Action of Otezla (Apremilast) Introduction Otezla is the brand name for apremilast, an oral phosphodiesterase-4 (PDE4) inhibitor used for the treatment of plaque psoriasis, psoriatic arthritis, oral ulcers associated with Behçet’s disease, and other inflammatory conditions. Unlike biologic therapies that target specific cytokines, apremilast works intracellularly by modulating inflammatory signaling pathways through cyclic … Read more

Mechanism of Action of Benzoyl Peroxide

April 10, 2026November 17, 2025 Pharmacy Freak Editorial Team Harsh Singh Rajput

Introduction Benzoyl peroxide is a topical antimicrobial and keratolytic agent widely used in the management of acne vulgaris. It is considered a first-line therapy for comedonal, inflammatory, and mild-to-moderate acne. Benzoyl peroxide is known for its powerful bactericidal activity, ability to reduce sebum, and its capacity to prevent antibiotic resistance when used with topical or … Read more