Introduction Bleomycin is a cytotoxic glycopeptide antibiotic used as an antineoplastic agent, especially in the treatment of Hodgkin lymphoma, testicular cancer, squamous cell carcinomas, and germ cell tumors. It is unique among chemotherapeutic agents because it causes minimal myelosuppression but is strongly associated with pulmonary toxicity. Bleomycin acts primarily during the G2 phase of the … Read more
Introduction Bisoprolol is a highly selective beta-1 adrenergic receptor blocker used extensively in the management of hypertension, chronic heart failure, angina pectoris, and arrhythmias. As a cardioselective beta blocker, bisoprolol primarily targets beta-1 receptors in the heart, exerting strong negative chronotropic, inotropic, and dromotropic effects with minimal influence on beta-2 receptors in the lungs and … Read more
Introduction Bismuth subsalicylate is an antidiarrheal, gastroprotective, and antimicrobial agent commonly used in the treatment of acute diarrhea, traveler’s diarrhea, dyspepsia, and H. pylori–associated gastritis. It is the active ingredient in many over-the-counter formulations used for stomach upset. Its mechanism of action is multifactorial, involving protection of the gastric mucosa, reduction of inflammation, inhibition of … Read more
Introduction Bisacodyl is a stimulant laxative widely used for the short-term relief of constipation, for bowel preparation before procedures, and for evacuation in conditions requiring rapid colonic emptying. It works by directly stimulating the enteric nervous system, increasing intestinal motility, and promoting fluid accumulation in the colon. As a potent bowel stimulant, bisacodyl acts primarily … Read more
Introduction Biguanides are a class of oral antihyperglycemic drugs, with metformin being the only widely used agent today. Metformin is the first-line therapy for type 2 diabetes mellitus due to its excellent safety profile, weight-neutral effect, and strong efficacy in lowering blood glucose without causing hypoglycemia. Mechanism of Action of Biguanides centers on decreasing hepatic … Read more
Introduction Betahistine is a histamine analogue used primarily in the treatment of Meniere’s disease, vertigo, and vestibular disorders. Its therapeutic effects involve improving microcirculation in the inner ear, enhancing vestibular compensation, and reducing endolymphatic pressure. Betahistine works through a dual mechanism: H1 receptor agonism (weak) and H3 receptor antagonism (strong), both contributing to symptomatic relief … Read more
Introduction Betahistine is a histamine analogue used primarily in the treatment of Meniere’s disease, vertigo, and vestibular disorders. Its therapeutic effects involve improving microcirculation in the inner ear, enhancing vestibular compensation, and reducing endolymphatic pressure. Betahistine works through a dual mechanism: H1 receptor agonism (weak) and H3 receptor antagonism (strong), both contributing to symptomatic relief … Read more
Introduction Benztropine is an anticholinergic and antihistaminic medication commonly used in the treatment of Parkinson’s disease and drug-induced extrapyramidal symptoms (EPS) such as dystonia, akathisia, and parkinsonism caused by antipsychotics. Its therapeutic effect comes from restoring the dopamine–acetylcholine balance in the basal ganglia. Benztropine blocks muscarinic receptors, reducing cholinergic activity, and provides antihistaminic sedation that … Read more
Introduction Benzoyl peroxide is a topical antimicrobial and keratolytic agent widely used in the management of acne vulgaris. It is considered a first-line therapy for comedonal, inflammatory, and mild-to-moderate acne. Benzoyl peroxide is known for its powerful bactericidal activity, ability to reduce sebum, and its capacity to prevent antibiotic resistance when used with topical or … Read more
Introduction Benzonatate is a non-narcotic antitussive (cough suppressant) commonly prescribed for symptomatic relief of acute cough in respiratory infections such as bronchitis, pneumonia, and influenza. Structurally related to ester-type local anesthetics like tetracaine, benzonatate works by numbing stretch receptors in the respiratory tract and reducing cough reflex sensitivity. Its unique mechanism provides cough relief without … Read more
