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Mechanism of Action of Biguanides

MOA of Biguanides

Introduction Biguanides are a class of oral antihyperglycemic drugs, with metformin being the only widely used agent today. Metformin is the first-line therapy for type 2 diabetes mellitus due to its excellent safety profile, weight-neutral effect, and strong efficacy in lowering blood glucose without causing hypoglycemia. Mechanism of Action of Biguanides centers on decreasing hepatic … Read more

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