Mechanism of Action of Bleomycin
Introduction Bleomycin is a cytotoxic glycopeptide antibiotic used as an antineoplastic agent, especially in the treatment of Hodgkin lymphoma, testicular cancer, squamous cell carcinomas, and germ cell tumors. It is unique among chemotherapeutic agents because it causes minimal myelosuppression but is strongly associated with pulmonary toxicity. Bleomycin acts primarily during the G2 phase of the … Read more