Introduction Rybelsus is the brand name of oral semaglutide, a glucagon-like peptide-1 receptor agonist used in the management of type 2 diabetes mellitus. It is pharmacologically important because it is an orally administered GLP-1 receptor agonist, unlike many other GLP-1 receptor agonists that are given by subcutaneous injection. Rybelsus is used along with diet and … Read more
Introduction Biguanides are a class of oral antihyperglycemic drugs, with metformin being the only widely used agent today. Metformin is the first-line therapy for type 2 diabetes mellitus due to its excellent safety profile, weight-neutral effect, and strong efficacy in lowering blood glucose without causing hypoglycemia. Mechanism of Action of Biguanides centers on decreasing hepatic … Read more
Introduction Linagliptin is an oral hypoglycemic drug belonging to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors. It is primarily used in the management of type 2 diabetes mellitus to improve glycemic control. Unlike many other antidiabetic agents, linagliptin has a unique excretion pathway, being mostly eliminated via the enterohepatic system rather than the kidneys, making … Read more
