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Mechanism of Action of Benztropine

MOA of Benztropine

Introduction Benztropine is an anticholinergic and antihistaminic medication commonly used in the treatment of Parkinson’s disease and drug-induced extrapyramidal symptoms (EPS) such as dystonia, akathisia, and parkinsonism caused by antipsychotics. Its therapeutic effect comes from restoring the dopamine–acetylcholine balance in the basal ganglia. Benztropine blocks muscarinic receptors, reducing cholinergic activity, and provides antihistaminic sedation that … Read more

Mechanism of Action of Anticholinergic Drugs

MOA of Anticholinergic Drugs

Introduction Anticholinergic drugs, also known as parasympatholytic agents, inhibit the actions of the neurotransmitter acetylcholine (ACh) at muscarinic receptors in the central and peripheral nervous systems. Mechanism of Action of Anticholinergic Drugs involves competitive antagonism of acetylcholine at muscarinic (M1–M5) receptor sites, thereby reducing parasympathetic activity. These drugs are used to treat disorders such as … Read more

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