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Mechanism of Action of Bethanechol

MOA of Bethanechol

Introduction Betahistine is a histamine analogue used primarily in the treatment of Meniere’s disease, vertigo, and vestibular disorders. Its therapeutic effects involve improving microcirculation in the inner ear, enhancing vestibular compensation, and reducing endolymphatic pressure. Betahistine works through a dual mechanism: H1 receptor agonism (weak) and H3 receptor antagonism (strong), both contributing to symptomatic relief … Read more

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