Introduction Fasenra is the brand name of benralizumab, a humanized monoclonal antibody used mainly in the management of severe eosinophilic asthma. It belongs to the class of biologic anti-eosinophilic therapies and is especially important in patients whose asthma remains uncontrolled despite standard inhaled corticosteroid and long-acting bronchodilator therapy. Unlike conventional asthma medicines such as beta-2 … Read more
Introduction Nucala is the brand name for mepolizumab, a humanized monoclonal antibody that targets interleukin-5 (IL-5). It is used for the treatment of severe eosinophilic asthma, eosinophilic granulomatosis with polyangiitis (EGPA), hypereosinophilic syndrome (HES), and chronic rhinosinusitis with nasal polyps. Eosinophils play a major role in eosinophilic inflammatory diseases by releasing inflammatory mediators that damage … Read more
Introduction Guaifenesin is an expectorant commonly used in the treatment of productive cough associated with respiratory tract infections such as bronchitis, the common cold, and other respiratory conditions. It works by reducing the viscosity of bronchial secretions, making mucus easier to clear from the airways. Unlike antitussive drugs that suppress cough reflexes, guaifenesin facilitates mucus … Read more
Introduction Bronchodilators are a broad class of drugs used to relieve bronchoconstriction, improve airflow, and treat respiratory disorders such as asthma, COPD, and bronchospasm. They work by relaxing airway smooth muscle, reducing airway resistance, and enhancing ventilation. The main drug classes that act as bronchodilators include: Each class uses a different mechanism, but all ultimately … Read more
Introduction Roflumilast is an oral selective phosphodiesterase-4 (PDE4) inhibitor used in the long-term management of severe chronic obstructive pulmonary disease (COPD) associated with chronic bronchitis. Unlike bronchodilators that target airway smooth muscle, roflumilast works primarily through anti-inflammatory mechanisms. Its distinct pharmacological action makes it a valuable adjunct in reducing the frequency of exacerbations in COPD … Read more
