Mechanism of Action of Nucala (Mepolizumab)
Introduction Nucala is the brand name for mepolizumab, a humanized monoclonal antibody that targets interleukin-5 (IL-5). It is used for the treatment of severe eosinophilic asthma, eosinophilic granulomatosis with polyangiitis (EGPA), hypereosinophilic syndrome (HES), and chronic rhinosinusitis with nasal polyps. Eosinophils play a major role in eosinophilic inflammatory diseases by releasing inflammatory mediators that damage … Read more