Mechanism of Action of Roflumilast
Introduction Roflumilast is an oral selective phosphodiesterase-4 (PDE4) inhibitor used in the long-term management of severe chronic obstructive pulmonary disease (COPD) associated with chronic bronchitis. Unlike bronchodilators that target airway smooth muscle, roflumilast works primarily through anti-inflammatory mechanisms. Its distinct pharmacological action makes it a valuable adjunct in reducing the frequency of exacerbations in COPD … Read more