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Mechanism of Action of Omeprazole

mechanism of action of omeprazole – proton pump inhibition in gastric parietal cells

Introduction Omeprazole is a commonly prescribed drug used to reduce gastric acid secretion. It belongs to the class of proton pump inhibitors (PPIs) and is widely used in the treatment of acid-related disorders. Due to its superior efficacy and tolerability, it has largely replaced H2 blockers in clinical practice. Omeprazole is primarily indicated in: Understanding … Read more

Mechanism of Action of Atorvastatin

Atorvastatin mechanism of action – HMG-CoA reductase inhibition and LDL receptor upregulation

🔍 Introduction Atorvastatin is a widely used lipid-lowering agent that belongs to the class of HMG-CoA reductase inhibitors, commonly known as statins. It is one of the most prescribed drugs worldwide due to its effectiveness in lowering LDL cholesterol and reducing cardiovascular risk. It plays a major role in: Because of its clinical importance and … Read more

Escitalopram – Mechanism of Action

Escitalopram mechanism of action – selective serotonin reuptake inhibition and enhanced serotonergic transmission

🔍 Introduction Escitalopram is a widely prescribed antidepressant belonging to the class of Selective Serotonin Reuptake Inhibitors (SSRIs). It is the S-enantiomer of citalopram and is considered one of the most selective SSRIs available. Escitalopram is mainly used to treat: Due to its clean pharmacological profile and importance in psychiatry, Escitalopram is frequently tested in … Read more

Paracetamol – Mechanism of Action

Paracetamol mechanism of action – central COX inhibition and antipyretic action via hypothalamus

Introduction Paracetamol (also known as Acetaminophen) is one of the most commonly used drugs for fever and mild-to-moderate pain. Unlike NSAIDs, it has minimal anti-inflammatory action and does not cause gastric irritation. It is classified as: Despite its widespread use, its exact mechanism of action has long been debated and is often misunderstood—making it a … Read more

Methotrexate – Mechanism of Action

Flowchart of Methotrexate mechanism of action showing DHFR inhibition and suppression of DNA synthesis in S-phase

Introduction Methotrexate is a cornerstone drug in both anticancer chemotherapy and immunosuppressive therapy. Structurally, it is a folic acid antagonist and functions as an antimetabolite. It is widely used in: Due to its dual role in oncology and immunology, Methotrexate is a high-yield topic in exams like GPAT, NIPER, NEET-PG, NCLEX, and essential for PharmD, … Read more

Aspirin – Mechanism of Action

Stepwise mechanism of action of Aspirin showing COX inhibition and antiplatelet effect

Introduction Aspirin, also known as acetylsalicylic acid, is a widely used Non-Steroidal Anti-Inflammatory Drug (NSAID). It’s primarily known for its analgesic (pain-relieving), antipyretic (fever-reducing), anti-inflammatory, and antiplatelet actions. Belonging to the salicylate class, Aspirin is often prescribed for: Due to its clinical importance and frequent exam presence, understanding its mechanism of action is essential for … Read more

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