Hyperkalemia Treatment - Pharmacy Freak

Mechanism of Action of Calcium Gluconate

April 10, 2026November 30, 2025 Pharmacy Freak Editorial Team Harsh Singh Rajput

Introduction Calcium gluconate is an intravenous and oral calcium supplement widely used for the management of hypocalcemia, cardiac membrane stabilization during hyperkalemia, calcium channel blocker toxicity, magnesium sulfate overdose, and neonatal hypocalcemic tetany. The Mechanism of Action of Calcium Gluconate primarily involves rapid elevation of extracellular calcium levels, leading to stabilization of neuronal and cardiac … Read more

Mechanism of Action of Lokelma (Sodium Zirconium Cyclosilicate)

July 4, 2025July 1, 2025 Pharmacy Freak Editorial Team Harsh Singh Rajput

Introduction Lokelma is an oral, non-absorbed potassium binder used to treat hyperkalemia. It works by selectively trapping potassium ions in the gastrointestinal tract, thereby lowering serum potassium levels and promoting potassium excretion via feces. Step-by-Step Mechanism of Action Pharmacokinetic Parameters Clinical Uses Adverse Effects Comparative Analysis Lokelma offers higher selectivity and fewer systemic effects than … Read more