Mechanism of Action of Acetazolamide
Introduction Acetazolamide is a carbonic anhydrase inhibitor with diuretic, antiglaucoma, anticonvulsant, and altitude sickness applications. It reduces bicarbonate reabsorption in the kidney, lowers intraocular and intracranial pressures, and helps correct metabolic alkalosis. Step-by-Step Mechanism of Action Pharmacokinetic Parameters Parameter Value Bioavailability Well absorbed Time to peak plasma ~1–4 hours Protein Binding ~70–90%derangedphysiology.com+15en.wikipedia.org+15reference.medscape.com+15ccforum.biomedcentral.com+3reference.medscape.com+3derangedphysiology.com+3 Metabolism None (excreted unchanged) … Read more