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Mechanism of Action of Opzelura

Mechanism of Action of Opzelura

Introduction Opzelura is the brand name of ruxolitinib cream, a topical Janus kinase inhibitor used in inflammatory and autoimmune skin diseases. It contains ruxolitinib phosphate and is available as a 1.5% cream for application to affected skin areas. Opzelura is indicated for the short-term and non-continuous chronic treatment of mild to moderate atopic dermatitis in … Read more

Mechanism of Action of Ruxolitinib

Mechanism of Action of Ruxolitinib

Introduction Ruxolitinib is an oral Janus kinase inhibitor used mainly in hematological and immune-mediated disorders. It is best known by the brand name Jakafi for systemic use, and it selectively inhibits Janus kinase 1 and Janus kinase 2, commonly called JAK1 and JAK2. Ruxolitinib is important in pharmacology because JAK enzymes are central mediators of … Read more

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