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Mechanism of Action of Olaparib

Mechanism of Action of Olaparib

Introduction Olaparib is an oral anticancer drug that belongs to the poly ADP-ribose polymerase inhibitor class, commonly called PARP inhibitors. It is marketed under the brand name Lynparza. Olaparib is an important targeted anticancer drug used in cancers with defects in DNA repair pathways, especially BRCA1, BRCA2, and other homologous recombination repair gene abnormalities. The … Read more

Mechanism of Action of Bicalutamide

mechanism of action of bicalutamide

Introduction Bicalutamide is a non-steroidal antiandrogen used primarily in the treatment of prostate cancer. It acts by blocking the action of androgens, which are critical in the development and progression of prostate malignancies. Unlike steroidal antiandrogens, bicalutamide offers selective androgen receptor antagonism with fewer hormonal side effects, making it an important drug in androgen deprivation … Read more

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