Introduction Relugolix is an oral gonadotropin-releasing hormone receptor antagonist, also called a GnRH receptor antagonist or LHRH receptor antagonist. It is used as relugolix alone under the brand name Orgovyx for adult patients with advanced prostate cancer. Relugolix is also present in the combination product Myfembree, which contains relugolix, estradiol, and norethindrone acetate for selected … Read more
Introduction Orgovyx is the brand name of relugolix, an oral hormonal anticancer drug used in adult patients with advanced prostate cancer. Pharmacologically, Orgovyx is a gonadotropin-releasing hormone receptor antagonist, also called a GnRH receptor antagonist or LHRH receptor antagonist. Prostate cancer growth is commonly driven by androgen signaling, especially testosterone and dihydrotestosterone. Testosterone is mainly … Read more
Introduction Orilissa is the brand name of elagolix, an oral nonpeptide gonadotropin-releasing hormone receptor antagonist used for the management of moderate to severe pain associated with endometriosis. Endometriosis is a chronic estrogen-dependent inflammatory disorder in which endometrial-like tissue grows outside the uterus, commonly on the ovaries, fallopian tubes, pelvic peritoneum, uterosacral ligaments, bowel, or bladder. … Read more
