NSAIDs - Pharmacy Freak

Mechanism of Action of Celecoxib

April 10, 2026December 8, 2025 Pharmacy Freak Editorial Team Harsh Singh Rajput

Introduction Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor used widely for pain, inflammation, and osteoarthritis/rheumatoid arthritis management. Unlike nonselective NSAIDs, celecoxib spares COX-1, reducing the risks of gastric irritation and gastrointestinal bleeding while providing potent anti-inflammatory and analgesic effects. The Mechanism of Action of Celecoxib centers on selective inhibition of COX-2, leading to decreased synthesis … Read more

Mechanism of Action of Aceclofenac

April 10, 2026October 4, 2025 Pharmacy Freak Editorial Team Harsh Singh Rajput

Introduction Aceclofenac is a widely used nonsteroidal anti-inflammatory drug (NSAID) indicated for pain relief and reduction of inflammation in musculoskeletal and joint disorders. Mechanism of Action of Aceclofenac primarily involves inhibition of cyclooxygenase (COX) enzymes, leading to reduced prostaglandin synthesis. It is often preferred for its relatively better gastrointestinal tolerability compared to some older NSAIDs. … Read more

Mechanism of Action of NSAIDs

June 30, 2025 Pharmacy Freak Editorial Team Harsh Singh Rajput

Introduction Non-steroidal anti-inflammatory drugs (NSAIDs) are a widely used class of medications with analgesic, anti-inflammatory, and antipyretic properties. They are commonly prescribed for pain relief, reducing inflammation in conditions like arthritis, dysmenorrhea, and fevers. NSAIDs achieve these effects by inhibiting cyclooxygenase enzymes involved in prostaglandin synthesis. Step‑by‑Step Mechanism of Action Pharmacokinetic Parameters Parameter Ibuprofen (Representative … Read more

CLASSIFICATION OF NON STEROIDAL ANTI INFLAMMATORY DRUGS

April 5, 2023March 11, 2023 Pharmacy Freak Editorial Team G S Sachin

NSAIDs It is also called ANTIPYRETIC-ANALGESICS or NSAIDs. NSAIDs are frequently used to treat pain, to reduce inflammation, and lower fever. They function by preventing the body from producing prostaglandins. Prostaglandinsare substances that contribute to inflammation and discomfort.Aspirin, ibuprofen, and naproxen are a few examples of NSAIDs. These drugs are very commonly used. Many medications … Read more