Mechanism of Action of Celecoxib
Introduction Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor used widely for pain, inflammation, and osteoarthritis/rheumatoid arthritis management. Unlike nonselective NSAIDs, celecoxib spares COX-1, reducing the risks of gastric irritation and gastrointestinal bleeding while providing potent anti-inflammatory and analgesic effects. The Mechanism of Action of Celecoxib centers on selective inhibition of COX-2, leading to decreased synthesis … Read more