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Mechanism of Action of Fingolimod

Fingolimod Mechanism of Action

Introduction Fingolimod is an oral disease-modifying drug used in relapsing forms of multiple sclerosis. It was originally marketed under the brand name Gilenya. Pharmacologically, fingolimod is a sphingosine 1-phosphate receptor modulator, commonly called an S1P receptor modulator. Multiple sclerosis is an immune-mediated demyelinating disease of the central nervous system. In MS, autoreactive lymphocytes cross the … Read more

Mechanism of Action of Kesimpta

Kesimpta Mechanism of Action

Introduction Kesimpta is the brand name of ofatumumab, a subcutaneous monoclonal antibody used for relapsing forms of multiple sclerosis. Pharmacologically, Kesimpta is a CD20-directed cytolytic antibody. It is used in adults with relapsing forms of multiple sclerosis, including clinically isolated syndrome, relapsing-remitting multiple sclerosis, and active secondary progressive multiple sclerosis. Multiple sclerosis is an immune-mediated … Read more

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