Mineralocorticoid Receptor Antagonist

Mechanism of Action of Kerendia (Finerenone)

June 17, 2026 Harsh Singh Rajput

Introduction Kerendia is the brand name for finerenone, a non-steroidal selective mineralocorticoid receptor antagonist (MRA) used to reduce the risk of chronic kidney disease (CKD) progression and cardiovascular complications in adults with chronic kidney disease associated with type 2 diabetes mellitus. Unlike older steroidal MRAs such as spironolactone and eplerenone, finerenone has a unique non-steroidal … Read more

Mechanism of Action of Eplerenone

April 10, 2026January 14, 2026 Pharmacy Freak Editorial Team Harsh Singh Rajput

Introduction Eplerenone is a selective mineralocorticoid receptor antagonist (MRA) used primarily in cardiovascular disorders such as heart failure and hypertension. It is a steroidal compound structurally related to spironolactone but with greater receptor selectivity, resulting in fewer endocrine adverse effects. From an exam and clinical standpoint, eplerenone is important due to its role in blocking … Read more