Mechanism of Action of Eplerenone
Introduction Eplerenone is a selective mineralocorticoid receptor antagonist (MRA) used primarily in cardiovascular disorders such as heart failure and hypertension. It is a steroidal compound structurally related to spironolactone but with greater receptor selectivity, resulting in fewer endocrine adverse effects. From an exam and clinical standpoint, eplerenone is important due to its role in blocking … Read more