Mechanism of Action of Nilotinib
Introduction Nilotinib is an oral anticancer drug used mainly in Philadelphia chromosome-positive chronic myeloid leukemia, commonly abbreviated as Ph+ CML. It belongs to the BCR-ABL tyrosine kinase inhibitor class. The most widely known brand name is Tasigna, and another formulation is Danziten. Nilotinib is pharmacologically related to imatinib but was designed to bind the BCR-ABL … Read more
