Mechanism of Action of Canakinumab
Introduction Canakinumab is a recombinant human monoclonal antibody used as a targeted anti-inflammatory biologic. It is marketed under the brand name Ilaris and belongs to the class of interleukin-1 beta inhibitors. Canakinumab specifically blocks interleukin-1 beta, also written as IL-1β, a powerful pro-inflammatory cytokine involved in fever, neutrophil recruitment, acute-phase response, joint inflammation, systemic inflammation, … Read more