Introduction Griseofulvin is an antifungal antibiotic primarily used to treat dermatophyte infections such as tinea infections of the skin, hair, and nails. It is derived from the mold Penicillium griseofulvum and works by inhibiting fungal cell division. Unlike many antifungal drugs that target the fungal cell membrane, griseofulvin acts on fungal microtubules and mitotic spindle … Read more
Introduction Antifungal drugs are pharmacological agents that target fungal infections (mycoses) of the skin, mucosa, and internal organs. Mechanism of Action of Antifungal Drugs centers on disruption of ergosterol synthesis, cell membrane integrity, cell wall formation, or nucleic acid synthesis. Fungi are eukaryotic, so selective toxicity is achieved by exploiting pathways unique to fungal cells, … Read more
Introduction Antifungal drugs are pharmacological agents used to treat fungal infections (mycoses) affecting the skin, mucous membranes, or internal organs. Mechanism of Action of Antifungal Drugs involves disruption of fungal cell membrane integrity, cell wall synthesis, or nucleic acid function. Since fungal cells are eukaryotic and share many structural similarities with human cells, antifungal agents … Read more
