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Mechanism of Action of Steroids

Mechanism of action of Steroids

Introduction Steroids, specifically corticosteroids such as prednisone, prednisolone, dexamethasone, hydrocortisone, and methylprednisolone, are potent anti-inflammatory and immunosuppressive agents. They mimic the actions of endogenous cortisol and regulate the expression of numerous genes involved in inflammation, immunity, metabolism, and stress responses. Corticosteroids are widely used in autoimmune diseases, allergic disorders, inflammatory conditions, organ transplantation, and many … Read more

Mechanism of Action of Glucocorticoids

Mechanism of Action of Glucocorticoids

Introduction Glucocorticoids are steroid hormones that regulate metabolism, immune responses, inflammation, and stress adaptation. Endogenous glucocorticoids such as cortisol are produced by the adrenal cortex, while synthetic glucocorticoids like prednisone, dexamethasone, and hydrocortisone are widely used in clinical medicine. Glucocorticoids exert their effects primarily through intracellular glucocorticoid receptors, altering gene transcription and protein synthesis. Their … Read more

Mechanism of Action of Corticosteroids

MOA of corticosteroids

Introduction Corticosteroids are a class of steroid hormones that exert potent anti-inflammatory, immunosuppressive, anti-allergic, and metabolic effects. They are synthetic analogs of endogenous glucocorticoids produced by the adrenal cortex, primarily cortisol. Corticosteroids are extensively used across multiple medical specialties, including internal medicine, pulmonology, dermatology, rheumatology, neurology, and critical care. Their broad mechanism of action at … Read more

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