Glucocorticoids - Pharmacy Freak

Mechanism of Action of Hydrocortisone

April 10, 2026March 16, 2026 Pharmacy Freak Editorial Team Harsh Singh Rajput

Introduction Hydrocortisone is a naturally occurring glucocorticoid hormone that is identical to cortisol produced by the adrenal cortex. It exhibits both glucocorticoid and mild mineralocorticoid activity and is widely used for its anti-inflammatory, immunosuppressive, and metabolic effects. Hydrocortisone is used clinically in conditions such as adrenal insufficiency, allergic reactions, autoimmune diseases, inflammatory disorders, and dermatologic … Read more

Mechanism of Action of Glucocorticoids

April 10, 2026March 5, 2026 Pharmacy Freak Editorial Team Harsh Singh Rajput

Introduction Glucocorticoids are steroid hormones that regulate metabolism, immune responses, inflammation, and stress adaptation. Endogenous glucocorticoids such as cortisol are produced by the adrenal cortex, while synthetic glucocorticoids like prednisone, dexamethasone, and hydrocortisone are widely used in clinical medicine. Glucocorticoids exert their effects primarily through intracellular glucocorticoid receptors, altering gene transcription and protein synthesis. Their … Read more