Mechanism of Action of Glucocorticoids
Introduction Glucocorticoids are steroid hormones that regulate metabolism, immune responses, inflammation, and stress adaptation. Endogenous glucocorticoids such as cortisol are produced by the adrenal cortex, while synthetic glucocorticoids like prednisone, dexamethasone, and hydrocortisone are widely used in clinical medicine. Glucocorticoids exert their effects primarily through intracellular glucocorticoid receptors, altering gene transcription and protein synthesis. Their … Read more