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Mechanism of Action of Cladribine

Mechanism of Action of Cladribine

Introduction Cladribine is a purine nucleoside analogue used as an immunosuppressive and antineoplastic drug. It is available under important brand names such as Mavenclad for relapsing forms of multiple sclerosis and Leustatin for hairy cell leukemia. Pharmacologically, cladribine is an adenosine analogue that is resistant to degradation by adenosine deaminase, allowing it to persist inside … Read more

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