Mechanism of Action of Dabrafenib
Introduction Dabrafenib is an oral targeted anticancer drug marketed under the brand name Tafinlar. Pharmacologically, dabrafenib is a BRAF kinase inhibitor used in selected cancers with activating BRAF mutations. The BRAF protein is a serine/threonine kinase in the RAS-RAF-MEK-ERK signaling pathway, also called the MAPK pathway. This pathway normally transmits growth signals from cell-surface receptors … Read more