Classification Of Anticholinargic Drugs

Anticholinergic drugs

Anticholinergic drugs are a class of medications that block the actions of acetylcholine, a neurotransmitter, in the central and peripheral nervous system.

Uses

They are used to treat a variety of conditions including:

• Overactive bladder syndrome
• Urinary incontinence
• Gastrointestinal conditions such as irritable bowel syndrome (IBS)
• Parkinson’s disease
• Chronic obstructive pulmonary disease (COPD)
• Motion sickness
• Allergic rhinitis
• Asthma
• Alcohol withdrawal symptoms

Classification

ANTICHOLINERGIC DRUGS (Muscarinic antagonists, Atropinic drugs, Parasympatholytics)

1. Natural alkaloids– Atropine, Hyoscine (Scopolamine)
2. Semisynthetic derivatives– Atropine methonitrate, Homatropine, Hyoscine butyl bromide, Ipratropium bromide, Tiotropium bromide
3. Synthetic compounds
   • Mydriatics– Cyclopentolate, Tropicamide
   • Vasicoselective– Oxybutynin, Flavoxate, Tolterodine
   • Antiparkinsonian– Trihexyphenidyl (Benzhexol), Procyclidine, Biperiden
   • Antisecretory-antispasmodics
     • Quaternary comps.– Propantheline, Oxyphenonium, Clidinium, Pipenzolate methyl bromide, Isopropamide, Glycopyrrolate,
     • Tertiary amines– Dicyclomine, Valethamate, Pirenzepine

Related Links

• Classification of Cholinergic drugs

Reference

• CLASSIFICATION OF DRUGS- KD Tripathi
• National Library of Medicine- ANTICHOLINERGIC DRUGS (Noah Ghossein; Michael Kang; Anand D. Lakhkar.)