Mechanism of Action of Gabapentin
Introduction Gabapentin is an anticonvulsant and analgesic drug primarily used in the treatment of epilepsy, neuropathic pain, and restless legs syndrome. Though structurally related to gamma-aminobutyric acid (GABA), gabapentin does not bind to GABA receptors or influence GABA metabolism. Instead, it modulates neuronal excitability by interacting with voltage-gated calcium channels. Its favorable safety profile and … Read more
