Introduction Rybelsus is the brand name of oral semaglutide, a glucagon-like peptide-1 receptor agonist used in the management of type 2 diabetes mellitus. It is pharmacologically important because it is an orally administered GLP-1 receptor agonist, unlike many other GLP-1 receptor agonists that are given by subcutaneous injection. Rybelsus is used along with diet and … Read more
Introduction Carbimazole is a thiourea-derived antithyroid drug used primarily in the management of hyperthyroidism, especially Graves’ disease, toxic multinodular goiter, and thyroid storm (as adjunct therapy). After oral administration, carbimazole is rapidly converted to its active metabolite methimazole, which exerts the therapeutic effects. The Mechanism of Action of Carbimazole involves suppression of thyroid hormone synthesis … Read more
Introduction Calcitonin is a peptide hormone produced by the parafollicular (C cells) of the thyroid gland and is also available as a therapeutic agent (salmon calcitonin). It plays an essential role in calcium and bone metabolism, acting as a physiological antagonist to parathyroid hormone (PTH). The Mechanism of Action of Calcitonin centers on inhibition of … Read more
Introduction Bromocriptine is a dopamine D2 receptor agonist used in the treatment of Parkinson’s disease, hyperprolactinemia, acromegaly, and type 2 diabetes mellitus (bromocriptine-QR). As an ergot-derived dopamine agonist, it mimics the action of dopamine on pituitary and central nervous system receptors. Its mechanism of action involves inhibiting prolactin secretion, activating dopaminergic pathways, and modulating hypothalamic … Read more
