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Mechanism of Action of Trodelvy (Sacituzumab Govitecan)

Introduction Trodelvy is the brand name for sacituzumab govitecan, an antibody-drug conjugate (ADC) used for the treatment of certain advanced or metastatic cancers, particularly triple-negative breast cancer (TNBC) and hormone receptor-positive/HER2-negative breast cancer after prior therapies. It combines the targeting capability of a monoclonal antibody with the potent cytotoxic activity of a chemotherapy payload. Sacituzumab … Read more

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