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Mechanism of Action of Antidepressant Drugs

MOA of Antidepressant Drugs

Introduction Antidepressant drugs are psychotropic agents used to treat major depressive disorder, anxiety, OCD, PTSD, and chronic pain syndromes. Mechanism of Action of Antidepressant Drugs centers around increasing synaptic concentrations of monoamine neurotransmitters—primarily serotonin (5-HT), norepinephrine (NE), and dopamine (DA)—within the central nervous system. These drugs act on transporters, enzymes, or receptors to restore neurochemical … Read more

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