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Mechanism of Action of Tetrabenazine

Tetrabenazine Mechanism of Action

Introduction Tetrabenazine is a centrally acting vesicular monoamine transporter 2 (VMAT2) inhibitor used primarily to manage hyperkinetic movement disorders. It is especially effective in reducing chorea associated with Huntington’s disease. By depleting monoamines such as dopamine from nerve terminals, it helps in restoring neurochemical balance in the basal ganglia. Mechanism of Action (Stepwise Points) Pharmacokinetics … Read more

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