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Mechanism of Action of Tetrabenazine

Tetrabenazine Mechanism of Action

Introduction Tetrabenazine is a centrally acting vesicular monoamine transporter 2 (VMAT2) inhibitor used primarily to manage hyperkinetic movement disorders. It is especially effective in reducing chorea associated with Huntington’s disease. By depleting monoamines such as dopamine from nerve terminals, it helps in restoring neurochemical balance in the basal ganglia. Mechanism of Action (Stepwise Points) Pharmacokinetics … Read more

Mechanism of Action of Alteplase

ALTEPLASE Mechanism of Action

Introduction Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent. It plays a crucial role in the dissolution of fibrin clots and is utilized primarily in acute ischemic stroke, myocardial infarction, and pulmonary embolism. This agent mimics the naturally occurring enzyme tissue plasminogen activator (tPA), facilitating clot breakdown and restoring blood … Read more

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