antihistamine drugs - Pharmacy Freak

Mechanism of Action of Cetirizine

April 10, 2026December 10, 2025 Pharmacy Freak Editorial Team Harsh Singh Rajput

Introduction Cetirizine is a second-generation antihistamine widely used for the management of allergic rhinitis, urticaria, and other allergic disorders. It is favored for its minimal sedative effects, long duration of action, and excellent safety profile. The Mechanism of Action of Cetirizine involves selective antagonism of peripheral H1 histamine receptors, reducing allergic symptoms such as itching, … Read more

Mechanism of Action of Antihistamine Drugs

April 10, 2026November 6, 2025 Pharmacy Freak Editorial Team Harsh Singh Rajput

Introduction Antihistamines are pharmacological agents that counteract the effects of histamine, a biogenic amine released during allergic and inflammatory responses. Mechanism of Action of Antihistamine Drugs involves competitive antagonism at histamine H₁ or H₂ receptors, thereby reducing vasodilation, vascular permeability, smooth muscle contraction, and gastric acid secretion. Clinically, antihistamines are used in the management of … Read more