Mechanism of Action of Antihistamine Drugs
Introduction Antihistamines are pharmacological agents that counteract the effects of histamine, a biogenic amine released during allergic and inflammatory responses. Mechanism of Action of Antihistamine Drugs involves competitive antagonism at histamine H₁ or H₂ receptors, thereby reducing vasodilation, vascular permeability, smooth muscle contraction, and gastric acid secretion. Clinically, antihistamines are used in the management of … Read more