antidepressants - Pharmacy Freak

Mechanism of Action of Venlafaxine

June 12, 2026 Harsh Singh Rajput

Introduction Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressant widely used in the treatment of major depressive disorder, generalized anxiety disorder, social anxiety disorder, and panic disorder. Unlike selective serotonin reuptake inhibitors (SSRIs), venlafaxine enhances both serotonergic and noradrenergic neurotransmission, providing broader modulation of mood-regulating pathways. Venlafaxine is often considered a dual-action antidepressant because its … Read more

Mechanism of Action of Fluoxetine

April 10, 2026January 24, 2026 Pharmacy Freak Editorial Team Harsh Singh Rajput

Introduction Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) widely used in the treatment of depressive and anxiety disorders. It was the first SSRI introduced into clinical practice and remains highly relevant due to its long half-life, activating profile, and extensive exam coverage. Fluoxetine is particularly important in pharmacology examinations because of its mechanism at … Read more

Mechanism of Action of Escitalopram

April 10, 2026January 16, 2026 Pharmacy Freak Editorial Team Harsh Singh Rajput

Introduction Escitalopram is a selective serotonin reuptake inhibitor (SSRI) widely prescribed for depressive and anxiety disorders. It is the S-enantiomer of citalopram and represents one of the most selective SSRIs available. Its clinical importance lies in its high efficacy, favorable tolerability, and minimal drug–drug interactions compared with older antidepressants. For medical and pharmacy examinations, escitalopram … Read more

Mechanism of Action of Duloxetine

April 10, 2026October 4, 2025 Pharmacy Freak Editorial Team Harsh Singh Rajput

Introduction Duloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI) widely used in psychiatry and neurology. It is prescribed for major depressive disorder, generalized anxiety disorder, neuropathic pain, fibromyalgia, and chronic musculoskeletal pain. Mechanism of Action of Duloxetine centers on its ability to modulate central monoaminergic neurotransmission by inhibiting reuptake of serotonin and norepinephrine. This dual mechanism … Read more