Amantadine

Introduction Amantadine is an antiviral agent and antiparkinsonian medication. Initially used for influenza A, it also treats drug-induced extrapyramidal symptoms and Parkinson’s disease. Its mechanism combines viral M2 ion channel inhibition and enhancement of dopaminergic neurotransmission in the central nervous system. Step-by-Step Mechanism of Action Pharmacokinetic Parameters Parameter Value Route Oral (capsule, syrup) Bioavailability ~86% … Read more