Mechanism of Action of Tacrolimus
Introduction Tacrolimus is a potent immunosuppressive agent widely used in organ transplantation and autoimmune diseases. It belongs to the calcineurin inhibitor class and suppresses T-lymphocyte activation by inhibiting interleukin-2 (IL-2) production. Tacrolimus is more potent than cyclosporine and plays a crucial role in preventing graft rejection after organ transplantation. Mechanism of Action (Step-wise) A key … Read more