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Mechanism of Action of Phenobarbital

MOA of Phenobarbital

Introduction Phenobarbital is a long-acting barbiturate used primarily as an anticonvulsant and sedative-hypnotic. It is widely used in the management of generalized tonic-clonic seizures and status epilepticus. Phenobarbital enhances inhibitory neurotransmission in the central nervous system, leading to decreased neuronal excitability and seizure control. Mechanism of Action (Step-wise) A key exam point is that phenobarbital … Read more

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