PDE3 inhibitors

Introduction Cilostazol is a phosphodiesterase-3 (PDE3) inhibitor used primarily for the treatment of intermittent claudication caused by peripheral arterial disease (PAD). It improves walking distance and reduces pain by promoting vasodilation and inhibiting platelet aggregation. The Mechanism of Action of Cilostazol involves inhibition of PDE3, resulting in increased cyclic adenosine monophosphate (cAMP) levels in platelets … Read more